GPC3 and hepatocellular carcinoma: When miR-132 was cotransfected with miR-520-3p, another tumor suppressive miRNA modulating GPC3, into the Huh-7 HCC cell line, the antiproliferative and proapoptotic functions of both miRNAs on the HCC cell line were shown to be enhanced by minimizing the level of YAP [63].