Though 16q-loss is frequently observed both in ductal and lobular carcinomas (with a slight higher frequency in lobular ones; see Figure 14), the CDH1 transcriptional difference between the two histotypes was detectable both in the presence (group A, B1, and D) or the absence of 16q-loss aberrations (CTRL group; Figure 13C). This evidence concerns the gene CDH1 and breast lobular carcinoma.