CRB1 and retinal degeneration: To define the tropism of different AAV capsids, 1 μL of 1 × 1013 gc/mL AAV2-CMV-GFP expression vectors packaged into three different AAV serotypes (AAV2/5.CMV.GFP, AAV2/9.CMV.GFP and AAV2/ShH10Y445F.CMV.GFP, called from now on AAV5, AAV9 and ShH10Y, respectively) were intravitreally or subretinally injected before retinal degeneration in P5 and P8 in control and Crb1 mutant rat retinas.