ABCA1 and type 2 diabetes mellitus: However, other works highlighted a similar [144] or even increased [145] CEC in T2DM patients compared to controls, suggesting a link to the degree of hypertriglyceridemia, usually associated with T2DM, that may act as a potent modulator of CEC by increasing the levels of preβ-HDL, specific cholesterol acceptors for ABCA1- mediated efflux.