Finally, it was demonstrated that countries where HLA-A*02:01 is the most frequent in the population had lower numbers of COVID-19 cases out of 106 population vs. countries where HLA-A*24:02 or HLA-A*11:01 are the most frequent alleles, as confirmed at two different time points (April 2020 p = 0.009 and August 2020 p = 0.013) [53]. This evidence concerns the gene HLA-A and COVID-19.