To investigate the relevance of the detected proangiogenic molecules CXCL2 and IL8 within glioma tissues on endothelial cell function, we performed various in vitro assays with endothelial cells from the periphery (Human Umbilical Vein Endothelial Cells, HUVEC) and the brain (Human Brain Microvascular Endothelial Cells, HBMEC). Here, CXCL8 is linked to central nervous system cancer.