Although it is believed that DDX5 is upregulated in several tumors compared with its levels in matched normal tissues [41], our PCTA and independent Oncomine analyses of two PCa datasets [42,43] revealed the downregulation of DDX5 expression in mCRPCa compared with its expression in primary PCa (Figure S4A,B). This evidence concerns the gene DDX5 and posterior cortical atrophy.