In tumor samples from 1144 NSCLC patients, PIK3CA mutations had an incidence of 3.7%, raised to 8.9% if counting only SCC [86], while in another cohort of 1117 NSCLCs, they were detected in 3.9% of SCCs and 2.7% of adenocarcinomas [87]. The gene discussed is PIK3CA; the disease is non-small cell lung carcinoma.