In a study that examined young Latin American breast cancer patients, TP53 mutations showed an unexpected pattern of mutations not common in breast cancer, where 27% of the mutations were single-base substitution-transversion mutations G:C > T:A compared to other young and old breast cancer cohorts used for comparison (METABRIC, TCGA, and International Agency for Research on Cancer IARC) [45]. The gene discussed is TP53; the disease is breast cancer.