Gremmel et al. [59] evaluated the evolution of high-sensitivity CRP, plasmatic P-selectin, D-dimer, and Doppler ultrasound in 44 patients with acute unprovoked DVT, both at diagnosis and after 1, 3, 6, and 12 months of follow-up, compared with a cohort of 88 healthy individuals. The gene discussed is SELP; the disease is deep vein thrombosis.