Differently from MCF-7 and MDA-MB-231 that derive from a pleural effusion, 8701-BC originate from an infiltrating ductal carcinoma before its metastatic effusion, and showed the highest expression of c10orf118 mRNA, suggesting a possible connection with cell metastasis and c10orf118 expression. Here, CCDC186 is linked to invasive ductal breast carcinoma.