Cluster 3: relatively high values for waist and BMI; highest levels for HOMA-IR, tro, GLU0, GLU60, GLU120, ALAT, ASAT, GGT, UA, IRI0, IRI60, IRI120, UFC. This might be described as a pattern of patients with pronounced insulin resistance, moderate central obesity, increased cortisol levels and hepatic disturbances. This evidence concerns the gene ABCB7 and Insulin resistance.