Similarly, as summarized in Table 1, the parental human OVCAR-8 ovarian cancer cells and human H460 lung cancer cells were also significantly more sensitive to citarinostat as compared to the respective ABCB1-overexpressing variant NCI-ADR-RES (R.F = 11) and ABCG2-overexpressing variants H460-MX20 (R.F = 3). The gene discussed is ABCB1; the disease is ovarian cancer.