CLEC10A and amyotrophic lateral sclerosis: Importantly, clinical trials are already ongoing to test if suppression of the HERV-K(HML-2) env protein using antiretroviral drugs [45] influences the neurophysiological outcomes of amyotrophic lateral sclerosis (ALS) symptoms, as the overexpression of the HERV-K(HML-2) env protein has been proposed as a possible causative factor in patients with ALS [19].