LDLR and familial hypercholesterolemia: Familial hypercholesterolemia (FH) (Online Mendelian Inheritance in Man-OMIM 143890) is an autosomal dominant genetic pathology, frequently caused by pathogenic variants of the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), and the proprotein convertase subtilisin/kexin type 9 (PCSK9) [1,2,3,4,5,6,7,8,9].