The c.502G > A mutation in exon 4 of LDLR gene was observed in few studies—in the UK in one patient [45], in Spain in one patient [46], in the Czech Republic in one subject [47], and in Canada in one subject [1] (Table 5), while in our study we identified the same mutation in one patient with new ASCVD (stroke). The gene discussed is LDLR; the disease is stroke disorder.