Thus, this study concluded that 5-FU sensitivity in CRC can be modulated via the DLGAP1-AS1/miR-149-5p/TGFB2 axis, however the authors stated that further work has to be carried out to further understand the relationship between DLGAP1-AS1 and TGFB2 as this was not investigated in dept [213]. This evidence concerns the gene DLGAP1 and colorectal carcinoma.