Peng et al. [262] investigated the role of PVT1 in cisplatin resistant CRC cells for both in vitro and in vivo conditions Similar to the results published by Fan et al. [198], PVT1 was highly expressed in CRC tissues and cell lines compared to the corresponding non-cancerous samples and normal colon epithelial cells. The gene discussed is PVT1; the disease is colorectal carcinoma.