NELFCD and neoplasm: Importantly, treatments with SCM in the absence or presence of polysaccharide fractions through 24 and 48 h incubation significantly (p < 0.05) inhibited the PC-3 cell viability (12.2 ± 2.8–29.4 ± 6.5%) as compared to those of controls (cells alone, about 100%), suggesting that splenocyte secretions (such as Th1/Th2 cytokines) in the tumor microenvironment may inhibit PC-3 cell growth (Figure 3).