In the present study, Th2-polarized and anti-inflammatory cytokine IL-10 either secreted by T lymphocytes in the splenocytes or peritoneal macrophages in the tumor microenvironment were correlated with Fas mRNA expression levels in the treated PC-3 cells (Figure 5 and Figure 6) [2,18,28,33]. The gene discussed is FAS; the disease is neoplasm.