Most of the leiomyoma DEGs were found upregulated in F compared to the MF or M (Figure 4F and Figure S2); however, some genes, including CDKN1A, L1CAM, SLC7A5, CCND1, IGF1R, and PTHLH, were only increased in MF vs. M and F vs. M comparisons (Figure 4E and Figure S2). The gene discussed is IGF1R; the disease is leiomyoma.