PCDH11X and leiomyoma: PCDH11X, an X-linked protocadherin gene involved in segmental development, was found upregulated in F vs. M and MF vs. M. The role of PCDH11X in leiomyomas is unclear, but hypomethylation of this gene has been reported in fibroids compared to the adjacent myometrium [20], which could lead to its overexpression.