Of the targets, ADRB2, CASP1, CCR5, CSF1R, MERTK, MMP2, and P2RX7 were significantly upregulated, and CDK5, CHRNB2, GRIN2B, GSK3B, and MAPK10 were significantly downregulated in AD patients compared to controls. The gene discussed is CSF1R; the disease is Alzheimer disease.