MiRmiR-328-3p inhibits metastasis in colorectal cancer via inactivation of the PI3K/Akt signaling pathway [58] and reduces invasion as well as EMT in liver cancer via by targeting endoplasmatic reticulum metallo protease 1 (ERMP1) to inhibit AKT phosphorylation [59]. This evidence concerns the gene AKT1 and colorectal cancer.