The association between mvE cells and expression of vessel- and S1P-related genes and gene sets in each mucinous adenocarcinoma and adenocarcinoma cohorts (Figures S7–S9) demonstrated mvE cell abundant CRC was significantly associated with worse overall survival (OS), disease-specific survival (DSS), and progression-free survival (PFS) in the TCGA cohort (Figure 5B; p = 0.038, 0.001, and 0.002, respectively). This evidence concerns the gene MBTPS1 and mucinous adenocarcinoma.