Some anti-diabetic drugs, which include glucagon-like peptide-1 receptor agonists (GLP-1RA) [22,23], sodium-glucose cotransporter-2 (SGLT-2) inhibitors [24,25], and PPARα agonists [26], have been reported to have an effect of reducing hepatic fat accumulation in human or rodent models of nonalcoholic steatohepatitis (NASH). The gene discussed is GLP1R; the disease is metabolic dysfunction-associated steatohepatitis.