PTK2 and breast carcinoma: Several circular RNAs, besides ciRS, also regulate miR-7 and its downstream targets: circHIPK3 in colorectal cancer, circ-0015756 in hepatocellular carcinoma influencing downstream FAK [43,44], hsa_circRNA_0006528 in breast cancer influencing proliferation through MAPK/ERK pathway [45], circ-U2AF1 in gliomas influencing the expression of NOVA 2 [46], circ-TFCP2L1 decreasing mir-7-PAK1 signaling [47], circAkap17b regulating FSH secretion in pituitary gland [48].