A 3-day course of Mexidol and Semax treatment did not significantly affect the total number of PGC-1α-immunopositive neurons, neurons with high and medium nuclear PGC-1α-immunoreactivity, compared to a single administration of drugs, but their numbers were higher by 30%, 4- and 1.4-fold, respectively, compared to those in the Stroke + Saline group (p < 0.05; Figure 7A,B, Figures S29 and S30). The gene discussed is PPARGC1A; the disease is Stroke.