Irrespectively of IgG/IgM level, the medium-high risk group self-reported higher probability of having experienced fever, cough, musculoskeletal pain, anosmia/ageusia, and chest pain during the outbreak period than comparators; no other significant difference of self-reported COVID-19-related symptoms was found between groups (Table 3). This evidence concerns the gene CD40LG and Anosmia.