PROS1 and acute respiratory distress syndrome: To assess whether the diminished lung inflammation mediated by AVR-25 and AVR-48 in ALI also impacted the production of lung adhesion molecules, endothelial adherens junction (AJ) proteins, and pulmonary edema, the expression of lung adhesion molecules intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, and E-selectin, were measured in whole lung tissues.