SLC5A9 and polycystic ovary syndrome: SGLT4 was upregulated in PCOS in both the cortex (3.89 ± 0.29 vs. 1.00 ± 0.12, p < 0.0001) and the medulla (3.27 ± 0.54 vs. 0.62 ± 0.09, p < 0.0001) (Figure 1F).