ACE and polycystic ovary syndrome: EMPA treatment significantly decreased renal medullary ACE activity in both control (4.828 ± 0.418 vs. 9.441 ± 0.856 nmol/min.mg protein, p < 0.0001) and PCOS groups (5.414 ± 0.885 vs. 9.965 ± 0.890 nmol/min.mg protein, p < 0.0001).