AGT and polycystic ovary syndrome: As shown in Figure 6B, in PCOS rats compared to controls, angiotensinogen mRNA was significantly upregulated in the renal medulla (19.17 ± 4.00 vs. 2.71 ± 0.40, p < 0.05) and elevated in the cortex without reaching significance by 3-way ANOVA (12.35 ± 4.80 vs. 1.00 ± 0.16, p = 0.298).