Korean researchers have shown that a heptapeptide of the protein kinase C delta (PKC-δ) catalytic V5 region binds to HSP27 in lung carcinoma NCI-H1299 cells, thereby impairing the HSP27-mediated tumor cell radioresistance in vitro [224] and in the xenografts growing in mice [225]. This evidence concerns the gene PRKCD and neoplasm.