HIF1A and glioblastoma: In another report [49], the hypoxia-induced radioresistance of glioblastoma cells was due to the HIF-1α-mediated expression of livin, an antiapoptotic protein, and this radioprotection can be blocked by the targeted inhibition of livin with the cell-permeable peptide TAT-Lp15 (TAT domain from human immunodeficiency virus-1 fused with the truncated peptide derived from linear peptides that specifically bind to livin).