Besides, the two oncogenes Multiple Copies in T-cell Malignancy 1 (MCT-1/MCTS1) and B lymphoma Mo-MLV insertion region 1 homolog (BMI1); HSF1 and molecular chaperones, including HSPs, GRPs and others; epigenetic regulator PR domain-containing protein M14 (PRDM14); microRNAs and long noncoding RNAs are involved in the formation/maintenance of a cancer stem phenotype (reviewed in [142,266,267]. The gene discussed is MCTS1; the disease is cancer.