A decrease in autophagy was correlated with the elevated radioresistance of hypoxic colorectal cancer cells [262] and cervical cancer cells in which autophagy was suppressed by MiR-21 via the Akt/mTOR signaling pathway [263] and dependent on the EGF receptor (EGFR) expression [264]. The gene discussed is EGFR; the disease is cervical carcinoma.