Twelve mRNAs (BCL3, IL1B, PTGS2, PTGES, PPARG, MMP11, CCR1, EGR1, CACNB4, CES1, IL8, S100A8) were able to differentiate between the control group and CRC, and five mRNAs (CES1, CXCL11, IL1B, ITGA2, NME1) identified large adenomas. This evidence concerns the gene CXCL8 and adenoma.