Twelve mRNAs (BCL3, IL1B, PTGS2, PTGES, PPARG, MMP11, CCR1, EGR1, CACNB4, CES1, IL8, S100A8) were able to differentiate between the control group and CRC, and five mRNAs (CES1, CXCL11, IL1B, ITGA2, NME1) identified large adenomas. Here, IL1B is linked to adenoma.