Twelve mRNAs (BCL3, IL1B, PTGS2, PTGES, PPARG, MMP11, CCR1, EGR1, CACNB4, CES1, IL8, S100A8) were able to differentiate between the control group and CRC, and five mRNAs (CES1, CXCL11, IL1B, ITGA2, NME1) identified large adenomas. The gene discussed is MMP11; the disease is adenoma.