To evaluate if the same expression profile and gene signatures were specifically characteristics of this rare subgroup of GIST, or if they were peculiar to neoplasms displaying the loss of function of SDH complex, we comparatively analyzed our microarray GIST series and a set of SDH-deficient pheochromocytoma and paraganglioma analyzed with the same protocol Affymetrix HG-U133 Plus 2.0 (available at E-MTAB-733 ArrayExpress). The gene discussed is SDHB; the disease is neoplasm.