VEGFA and age-related macular degeneration: Both the Comparison of AMD Treatments Trial (CATT) [2,3] and a real-world analysis that employed the Intelligent Research in Sight (IRIS) registry [4] confirmed that baseline visual acuity (VA) at the time of conversion from AMD to nAMD is a strong predictor of long-term visual outcomes under treatment with intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapies.