In contrast, Mfge8 KO mice treated with rMFG-E8 exhibited less severe inflammatory cell infiltration and reduction of acinar cell necrosis in the pancreas (Figure 5A), suggesting that rMFG-E8 attenuated cerulein-induced acute pancreatitis in Mfge8 KO mice. The gene discussed is MFGE8; the disease is acute pancreatitis.