Apart from sTGFβR3, the tumor-suppressive role of TGFβR3 was examined in a subcutaneous tumor model in nude mice, induced by the HCC cell-line MHCC97L, which was over-expressed with TGFβR3 (MHCC97L-TGFβR3). The gene discussed is TGFBR3; the disease is neoplasm.