SOD2 and alcoholic liver cirrhosis: Interestingly, a study on a Han-Chinese population (80 patients with alcoholic cirrhosis, 80 patients with alcoholic non-cirrhosis, 80 with viral hepatitis B-related cirrhosis and 165 healthy controls) has demonstrated that patients with alcoholic cirrhosis had a higher frequency of the SOD2 C/C and C/T genotypes than the other groups, suggesting that the SOD2 47T > C genetic variant is a risk factor for alcoholic cirrhosis susceptibility [135].