Analysis of the PanALL data set [26], which comprises 1988 B-ALL cases, validated the findings, and also revealed a strong expression in novel subtypes such as NUTM1-rearranged, PAX5-altered, ETV6-RUNX1-like, BCL2/MYC, and CRLF2 (Figure 3C). This evidence concerns the gene RUNX1 and precursor B-cell acute lymphoblastic leukemia.