IFNG and herpes zoster: Compared with LNP vaccines with encapsulated nucleic acid immunostimulators, LNP vaccines alone (LNP-gE) and the alum adjuvant induced very low CMI according to our ELISPOT analyses of both IFN-γ and IL-2, which suggested the potency of LNP-encapsulated gE and nucleic acid immunostimulators as zoster vaccines.