The expression of HSP-70, c-Myc, Bcl-2, Mcl-1, xIAP, and Bcl-xL, as well as other molecules, such as phosphatidylinositol, ERK, MAPK, chemokines, cell surface receptors, and G proteins in lymphoma cell-derived EVs, has also been linked to resistance to immunotherapy [111]. This evidence concerns the gene MYC and lymphoma.