It has also been documented that exosomes derived from Diffuse Large B Cell Lymphoma (DLBCL) cell lines (OCI-LY3, SU-DHL-16 (human DLBCL cell lines), and Raji cells (human Burkitt lymphoma cells) display malignancy molecules, such as c-Myc, Bcl-2, Mcl-1, CD19, and CD20, and mainly act as an immunosuppressive mediator, thereby promoting tumor growth in vivo. This evidence concerns the gene MYC and diffuse large B-cell lymphoma.