Sulforaphane-induced hormetic activation of Nrf2 provides the possibility of reducing the wide range of human-related neurological pathologies in the experimental disease models on Alzheimer’s disease (AD) [9], Parkinson’s disease [10], Huntington’s disease [11], amyotrophic lateral sclerosis [12], multiple sclerosis [13], autism spectrum disorder (ASD) [14], and schizophrenia [15]. Here, NFE2L2 is linked to Alzheimer disease.