PDE6B and eye infection: To further establish this differential transit across the BRB, we injected an equally mixed population of WT and RD1 mutant Mm into kdrl larvae, where we again found that at 4 dpi, WT Mm had already crossed the BRB in 52.9% (9/17) of the ocular infections, while RD1 mutant Mm remained present in the blood vessels in all larvae with ocular infections (n = 4) (Figure 7).