ADGRL3 and colorectal carcinoma: Similarly, when PLOD2 levels were suppressed by expression of a shRNA to PLOD2, the proliferation (Figure 2F, compare L1 to L1 + shPLOD2 cl2 and cl3) and motility (Figure 2G, compare L1 to L1 + shPLOD2 cl2 and cl3) of such CRC cells were reduced to the level observed in the control pcDNA3-transfected LS 174T cells.