These different CRC cell clones displayed the expected increase, or decrease, in PLOD2 levels as compared to the control (pcDNA3)-expressing and L1-expressing CRC cell clones (Figure 2A, compare lanes 5 and 6 to lane 1, lanes 3 and 4 to lane 2 and lanes 7–9 to lane 2). The gene discussed is PLOD2; the disease is colorectal carcinoma.