LRRK2 and Parkinson disease: A case-control study conducted by the International LRRK2 Consortium, which included 1,045 people with LRRK2 mutations in 133 families, estimated that the cumulative risk of PD for LRRK2 G2019S carriers was 28% at 59 years, 51% at 69 years, and 74% at 79 years of age [13].