Similar to EGCG administration, TEMPOL attenuated Dex-programmed increases in catecholamine related enzymes; PAH (1.2-fold), TH (1.8-fold), DBH (2.0-fold), and PNMT (1.4-fold); however, DBH and TH remain elevated compared to control in males (Figure 4A,C,E,G). The gene discussed is TH; the disease is pulmonary arterial hypertension.