Several studies have reported lncRNAs to be selectively packaged in exosomes for their biological functioning in recipient cells and could serve as biomarkers for various cancers such as PTENP1 (bladder cancer), MALAT1 (non-small cell lung cancer and breast cancer), HOTAIR (laryngeal squamous cell carcinoma), GAS5 (colorectal cancer), TUG1 and CCND1(cervical cancer and breast cancer) CCAT2 and POU3F3 (glioma), lnc-ROR, lnc-ROR, lnc TUC339 and lnc VLDLR (hepatocellular carcinoma) [40,67,69,70,71,72,73]. Here, HOTAIR is linked to breast cancer.