YAP1 and neoplasm: Based on the TCGA Pan-cancer cohort, we observed that the correlation pattern between YAP activity (reflected by curated YAP/TAZ downstream target score) and PD-L1 expression displays the highest in MPM (Figure S4A), suggesting that tumor-derived microenvironment may play a role in regulating PD-L1 in addition to YAP signaling.