The same authors reported another study that investigated the involvement of HMOX1 polymorphism in the responsiveness to antihypertensive treatment in preeclampsia patients and revealed that the TT genotype of A(-413)T SNP was more frequent in methyldopa–non-responsive patients than in responsive patients (30% vs. 11%, p = 0.02) [49]. Here, HMOX1 is linked to preeclampsia.