In diffuse large B cell lymphoma, activation-induced cytidine deaminase (AID) cooperates with TET2 binding to the FANCA promoter and thus increasing the expression of FANCA. Because of these results, the authors of the study proposed the combined use of AID and TET2 depletion in addition to bortezomib to better manage diffuse large B cell lymphoma [73]. The gene discussed is FANCA; the disease is diffuse large B-cell lymphoma.