Increased expression of miR-92a-3p contributes to the EMT and metastasis in colorectal cancer through activation of the Wnt/β-catenin pathway and inhibition of mitochondrial apoptosis [68] as well as in hepatocellular carcinoma and malignant retinoblastoma through the PTEN/Akt pathway [69,70]. This evidence concerns the gene AKT1 and retinoblastoma.