In Border Collies, for instance, Ubiquitin Specific Peptidase 31 (USP31) and RB Binding Protein 6 (RBBP6) have been associated with adult-onset deafness [13], whereas in the Doberman Pinscher, an insertion in Protein Tyrosine Phosphatase Receptor Type Q (PTPRQ) and a missense variant in Myosin VIIA (MYO7A) have been shown to be causative for a form of deafness that includes vestibular disease [14,15]. The gene discussed is USP31; the disease is deafness.