In addition, TRPA1 has been reported to promote the inflammatory response and itch in models of allergic contact dermatitis, atopic dermatitis and cytokine-induced itch [23,24,25,26,27], while a protective role has been suggested for TRPA1 in the imiquimod-induced model of psoriasiform dermatitis [28]. The gene discussed is TRPA1; the disease is atopic eczema.