Angiogenesis occurs under physiological conditions during normal wound healing and also in pathological contexts, such as tumorigenesis, so that antiangiogenic molecules (e.g., of Bevacizumab, an anti-vascular endothelial growth factor (VEGF) monoclonal antibody) are used in the treatment of different cancers, including HCC, according to recent guidelines [2]. Here, VEGFA is linked to cancer.